Principal Investigator

Center for Bioengineering
Center for Engineered Materials and Manufacturing (CEMM)
Center for Micro and Nanotechnology
Materials Engineering Division

Research Interests

1. Additive manufacturing and advanced materials development: Focus areas in photopolymer 3-D micromanufacturing techniques, optical systems, and micro-architected materials.
2. Biological instrumentation, bioengineering, and biomedical microtechnology: Ongoing development efforts include microfluidic approaches for the rapid separation, processing, analysis, and detection of biological targets; engineered systems for in vitro and ex vivo tissue culture.

Prior work

Implantable neural electrodes for stimulation and recording with applications in investigative neuroscience as well as therapeutics and prosthetics. Low-cost atomic force microscopy for the undergraduate laboratory.

Patents

• U.S. Pat Application #16/927,469 (2020) Computed Axial Lithography Optimization System
• U.S. Pat. Application # 15/930,822 (2019) Photocurable Resins for Volumetric Additive Manufacturing
• US Pat. Application # 15/651,861 (2017) Holographically-controlled Multi-Beam Volumetric Resist Curing Method And System For Additive Manufacturing
• US Patent #10,647,061 (2020) System and Method for Computed Axial Lithography (CAL) for 3D Additive Manufacturing
• US Pat. Application #15/244,605 (2016) System and Method For Stimulated Emission Depletion Projection Stereolithography
• US Patent #8,999,129 B2 (2015) Liquid and Liquid-filled Porous Electrodes for Electrophoresis
• US Patent #8,727,129 B2 (2014) Microfluidic Ultrasonic Particle Separators With Engineered Node Locations and Geometries
• US Pat. #8,524,064 B2 (2013), US Pat. #8,900,434, (2014) Three Dimensional Microelectrode System for Dielectrophoresis

Ph.D. Electrical Engineering, Massachusetts Institute of Technology, 2017

M.S. Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 2003

B.S.E. Electrical Engineering, Princeton University, 2001

• C. C. Cook, E. J. Fong, J. J. Schwartz, D. H. Porcincula, A. C. Kaczmarek, J. S. Oakdale, B. D. Moran, K. M. Champley, C. M. Rackson, A. Muralidharan, R. R. McLeod, M. Shusteff, "Highly Tunable Thiol?Ene Photoresins for Volumetric Additive Manufacturing," Adv Mater 2003376 (2020).
• J. J. Karnes, T. H. Weisgraber, J. S. Oakdale, M. Mettry, M. Shusteff, J. Biener, "On the Network Topology of Crosslinked Acrylate Photopolymers: A Molecular Dynamics Case Study," J Phys Chem B, 124(41), 9204–15 (2020).
• B. E. Kelly, I. Bhattacharya, H. Heidari, M. Shusteff, C. M. Spadaccini, H. K. Taylor, "Volumetric additive manufacturing via tomographic reconstruction," Science 363(6431), 1075-1079 (2019).
• M. D. Porter, B. Giera, R. M. Panas, L. A. Shaw, M. Shusteff, and J. B. Hopkins, "Experimental characterization and modeling of optical tweezer particle handling dynamics," Applied Optics 57(22), 6565-71 (2018).
• M. Shusteff, A. E. M. Browar, B. E. Kelly, J. Henriksson, T. H. Weisgraber, R. M. Panas, N. X. Fang, C. M. Spadaccini, "One-step volumetric additive manufacturing of complex polymer structures," Sci. Advances Vol. 3, no. 12, eaao5496 (2017).
• B. Kelly, I. Bhattacharya, M. Shusteff, R. M. Panas, H. K. Taylor, C. M Spadaccini "Computed Axial Lithography (CAL): Toward Single Step 3D Printing of Arbitrary Geometries," arXiv:1705.05893 (2017).
• L. A. Shaw, S. Chizari, R. M. Panas, M. Shusteff, C. M. Spadaccini, and J. B. Hopkins, "Holographic optical assembly and photopolymerized joining of planar microspheres," Optics Letters 41(15), 3571-3574 (2016).
• M. Shusteff, J. K. Dudoff, A. E. M. Browar, L. A. Shaw, R. M. Panas, J. B. Hopkins, N. X. Fang, C. M. Spadaccini "Optimal Source Beam Shaping for Digital Holographic Lithography," in Proc.of the 2016 Imaging and Applied Optics Congress, Heidelberg, Germany, DW1D.2 (2016).
• M. Shusteff, R. M. Panas, J. Henriksson, B. E. Kelly, A. E. M. Browar, N. X. Fang, and C. M. Spadaccini, "Additive Fabrication of 3D Structures by Holographic Lithography," in Proceedings of the 27th Annual Solid Freeform Fabrication Symposium, Austin, TX, 1183-1192 (2016)
• N. B. Zuckerman, M. Shusteff, P. F. Pagoria and A. E. Gash "Microreactor Flow Synthesis of the Secondary High Explosive 2,6-Diamino-3,5-dinitropyrazine-1-oxide (LLM-105)," J. Flow Chemistry 5(3) 178-182 (2015).
• E. J. Fong, C. Huang, J. Hamilton, W. J. Benett, M. Bora, A. Burklund, T. R. Metz, M. Shusteff  "A Microfluidic Platform for Precision Small-Volume Sample Processing and its Use to Size Separate Biological Particles With an Acoustic Microdevice" J. Visualized Experiments 105, e53051 (2015).
• M. Bora and M. Shusteff, "coupling of acoustic modes in microfluidic channel devices" Lab on a Chip, 15(15), 3192-3202 (2015).
• S.-Y. Jung, T. Notton, E. J. Fong, M. Shusteff, and L. S. Weinberger, "Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting" Lab on a Chip, 15(4), 1000-1003 (2015).
• X. Zheng, H. Lee, T. H.Weisgraber, M. Shusteff, J. Deotte, E. B. Duoss, J. D. Kuntz, M. M. Biener, Q. Ge, J. A. Jackson, S. O. Kucheyev, N. X. Fang, C. M. Spadaccini, "Ultralight, Ultrastiff Mechanical Metamaterials" Science, 344(6190), 1373-1377 (2014).
• E. J. Fong, A. C. Johnston, T. Notton, S.-Y. Jung, K. A. Rose, L. S. Weinberger, M. Shusteff, "Acoustic Focusing With Engineered Node Locations for High-Performance Microfluidic Particle Separation" Analyst, 139(5), 1192-1200 (2014).
• M. M. Packard, E.K. Wheeler, E. C. Alocilja, M. Shusteff, "Performance evaluation of fast microfluidic thermal lysis of bacteria for diagnostic sample preparation" Diagnostics 3(1), 105-116 (2013).
• Invited presentation: "Ignoring the Detector: Fast, Modular, Agnostic Sample Preparation" The Knowledge Foundation’s  Integrating Sample Preparation Conference 2011, Dec 8-9, 2011 Washington, DC
• M. Shusteff, H.-Y. Cheng, C. Hoyle, P. H. Paul, D. W. Arnold "Real-time enzyme reaction monitoring and kinetics measurements on the expressLC platform," 14th Annual Conference of the Society for Biomolecular Sciences, June 6, 2008, St. Louis, MO.
• M. Shusteff, T. P. Burg, S. R. Manalis,  "Measuring Boltzmann's constant with a low-cost atomic force microscope: an undergraduate experiment,"  American Journal of Physics 74(10),  873-879 (2006).
• T. Atanasijevic, M. Shusteff, P. Fam, A. Jasanoff, "Calcium Sensors for Magnetic Resonance Imaging Based on Superparamagnetic Iron Oxide Nanoparticles and Calmodulin,"  Proceedings of the National Academy of Science USA 103(40), 14707-14712 (2006).

• R&D 100 Award 2013 (DNATrax)
• Popular Mechanics Breakthrough Innovation Award 2013 (Artificial Retina)
• R&D 100 Award 2009 (Artificial Retina)