Janghyuk Lee

Portrait of  Janghyuk Lee

  • Title
    Staff Scientist
  • Email
    lee1071@llnl.gov
  • Phone
    (925) 423-4644
  • Organization
    PLS-MSD-MATERIALS SCIENCE DIVISION

Research Interests

  • Laser Physics (Confined Laser Ablation, Light Matter Interaction, Ultrafast Phenomenon)
  • Laser Spectroscopy
  • Laser Microscopy
  • High-speed Imaging
  • Nonlinear Optics
  • Biomedical Optics

Current position(s)

  Staff Scientist at Laser Materials Interaction Science group, MSD, PLS

Career path

  • 2019-2021 Postdoctoral Staff Research Member, Lawrence Livermore National Laboratory
  • 2019-2019 Postdoctoral Research Fellow, Harvard Medical School
  • 2016-2019 Postdoctoral Research Fellow, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
  • 2015-2016 Postdoctoral Research Fellow, Max Planck Institute for Polymer Research, Germany

Expertise

  • Coherent Vibrational Raman Microspectroscopy: Coherent anti-Stokes Raman Scattering (CARS), Stimulated Raman Scattering (SRS)
  • Raman Spectroscopy, Transient absorption spectroscopy (TAS)
  • Multiphoton Microscopy: Two and Three-photon Excitation Microscopy (2PEF, 3PEF), Second Harmonic Generation (SHG), Third Harmonic Generation (THG)
  • Fluorescence Lifetime Imaging Microscopy (FLIM)
  • Super Resolution Microscopy
  • Fiber Optics (Photonic Crystal Fiber)
  • Optical Coherence Tomography (OCT)

 

Ph.D., Physics (Optics and Laser), Gwangju Institute of Science and Technology (GIST), 2015

M.S., Physics (Optics and Laser), Gwangju Institute of Science and Technology (GIST), 2010

  1. S, Ly, J. Lee, A. M. Rubenchik, J. C. Crowhurst, C. D. Boley, V. N. Peters, W. J. Keller, “Tamper Performance for Confined Laser Drive Applications” Accepted in Optics Express (2023).
  2. J. Lee, R. Hestin, E. Nuccio, K. Morrison, C. Ramon, T. Samo, J. Pett-Ridge, Sonny Ly, T. Laurence, P. Weber, “Label-Free Multiphoton Imaging of Microbes in Root, Mineral, and Soil Matrices with Time-Gated Coherent Raman and Fluorescence Lifetime Imaging”, Environ. Sci. Technol. 56, 3, 1994–2008 (2022).
  3. D. Wang, L. Poyneer, D. Chen, S. Mark Ammons, K. Morrison, J. Lee, S. Ly, T. Laurence, and P. Weber, "Wavefront shaping with a Hadamard basis for scattering soil imaging," Appl. Opt.  61, F47-F54 (2022).
  4. J. Lee, S. S. Ly, T. A. Laurence, and P. K. Weber, "Label-free multiphoton nonlinear microspectroscopy imaging of microbial cells and organic matter in rhizosphere and soil minerals," in Label-Free Biomedical Imaging and Sensing (LBIS), SPIE, 11655, p. 21. (2021).
  5. S. Sternisha, P. Mukherjee, A. Alex, E. Chaney, R. Barkalifa, B. Wan, J. Lee, J. Rico‐Jimenez, S. A Sripada, M. Marjanovic, Z. Arp, S. Galosy, D. S Bhanushali, S. Hood, S. Bose, S. A Boppart, “Longitudinal monitoring of cell metabolism in biopharmaceutical production using label‐free fluorescence lifetime imaging microscopy,” Biotechnology Journal, 16 (2021).
  6. J. Rico-Jimenez*, J. Lee*, A. Alex, S. Musaad, E. Chaney, R. Barkalifa, E. Olson, D. Adams, M. Marjanovic, Z. Arp, and S. A. Boppart, "Non-invasive monitoring of pharmacodynamics during the skin wound healing process using multimodal optical microscopy," BMJ Open Diabetes Research and Care 8(1), e000974 (2020).
  7. J. Lee, J. Rico-Jimenez, C. Zhang, A. Alex, E. Chaney, R. Barkalifa, D. Spillman, M. Marjanovic, Z. Arp, S. Hood, and S. Boppart, "Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin," Biomed. Opt. Express  10, 5431-5444 (2019).
  8. J. Lee, D. H. Kim, W. K. Song, M.-K. Oh, and D.-K. Ko, "Label-free imaging and quantitative chemical analysis of Alzheimer’s disease brain samples with multimodal multiphoton nonlinear optical microspectroscopy," Journal of Biomedical Optics 20(5), 056013 (2015).
  9. J. Kim*, J. Lee*, and D.-K. Ko, "Determination of degree of unsaturation in edible oils using coherent anti-Stokes Raman scattering spectroscopy," Journal of Raman Spectroscopy 45(7), 591–595 (2014).
  10. J. Lee, J. C. Kim, G. Tae, M. Oh, and D.-K. Ko, "Rapid diagnosis of liver fibrosis using multimodal multiphoton nonlinear optical microspectroscopy imaging," Journal of Biomedical Optics 18(7), 076009 (2013).
  11. J. Lee, E. H. Cho, S. M. Shin, M. K. Oh, and D. K. Ko, "Comparative study of breast normal and cancer cells using coherent anti-stokes raman scattering microspectroscopy imaging," Applied Physics Express 5(8), 082401 (2012).
  • 2015-2016 Max Planck Postdoctoral Fellowship grant, Max Planck Institute, Germany
  • 2008 –2015 Received full National scholarship for M.S. and Ph.D. under Ministry of Science, ICT & Future Planning from the Korean Government
  • 2012 Outstanding Paper Award, Korea Physical Society Annual Meeting
  • 2011 Outstanding Paper Award, Advanced Laser and Their Applications Annual Meeting
  • 2011 Outstanding Paper Award, Optical Society of Korea Annual Meeting
  • 2009 Outstanding Paper Award, Korea Physical Society Annual Meeting
  • 2008 Chonbuk National University, Graduation Award, Summa cum laude
  • 2007 First prize at Intellectual Property Competition, Korean Intellectual Property Office
  • 2004 – 2008 Received 4 years full scholarship, Chonbuk National University

Memberships

  • Optical Society of America
  • SPIE – The International Society for Optics and photonics