Research

My research interests are in synthetic and systems biology and biochemistry. I am currently working on designing and engineering gene circuits in microbes for production of therapeutic molecules.

Ph.D. in Chemical Engineering, Massachusetts Institute of Technology, 2012

B.S. in Chemical Engineering, Seoul National University, 2005

Lee, TH., Carpenter, TS., D'haeseleer, P., Savage, DF., and Yung, MC. (2019) Encapsulin carrier proteins for enhanced expression of antimicrobial peptides. Biotechnology and Bioengineering

Lee, TH., and Maheshri, N. (2012) A regulatory role for repeated decoy transcription factor binding sites in target gene expression. Molecular Systems Biology 8: 576.

Yang, YH., Kang, YB., Kim, DH., Lee, TH., Park, SH., Lee, KW., Yoo, DW., Liou, KK., Lee, HC., Sohng, JK., and Kim, BG. (2010) One-pot enzymatic synthesis of deoxy-thymidine-diphosphate (TDP)-2-deoxy-α-D-glucose using phosphomannomutase. Journal of Molecular Catalalysis B: Enzymatic 62(3-4): 282-287.

Lee, MH., Lim, HR., Lee, TH., and Park, JC. (2009) Preparation of PLGA Microparticles by a Double Emulsion Solvent Technique for Sustained Release of (-)-epigallocatechin Gallate (EGCG) and Their Growth Inhibitory Effect on Rat Aortic Smooth Muscle Cells. Biomaterials Research 13(1): 11-15

Chung, JH., Lim, HR., Lee, TH., Lee, MH., Woo, YI., Baek, HS., Lee, SJ., Kim, JK., and Park, JC. (2007) Growth of smooth muscle cell and endothelial cell on PLGA Film containing EGCG. Key Engineering Materials 342-243: 93-96.

Yang, YH., Lee, TH., Kim, JH., Kim, EJ., Joo, HS., Lee, CS., and Kim, BG. (2006) High-throughput detection method of quorum sensing molecules by colorimetry and its applications. Analytical Biochemistry 356(2): 297-299.

Yang, YH., Kang, YB., Lee, KW., Lee, TH., Park, SS., Hwang, BY., and Kim, BG. (2005) Characterization of GDP-mannose pyrophosphorylase from Escherichia coli O157:H7 EDL933 and its broad substrate specificity. Journal of Molecular Catalalysis B: Enzymatic 37(1-6): 1-8.