Magdalena Franco

Research Scientist
Bioscience and Biotechnology Division
Email: franco14@llnl.gov
Phone: +19254230774

Education and professional experience

Biomedical Researcher, Bioscience and Biotechnology, Lawrence Livermore National Laboratory (2018-present)

Postdoctoral Fellow, Bioscience and Biotechnology, Lawrence Livermore National Laboratory (2018)

Postdoctoral Fellow, Microbiology and Immunology, Stanford University (2015)

Ph.D. Microbiology and Immunology, Stanford University (2014)

B.S. Microbiology and Chemistry, San Jose State University (2009)

 

Research interests

Microbial pathogenesis of emerging pathogens and biothreat agents, host immune response modeling and use of predictive biology for vaccine development.

 

Publications

Franco M, D'haeseleer P, Branda S, Liou M, Haider Y, Segelke B, El-Etr S. Proteomic profiling of Burkholderia thailandensis during host infection using bio-orthogonal noncanonical amino acid tagging (BONCAT). (2018) Front. Cell. Infect. Microbiol. 8, 370. 

Marino ND, Panas MW, Franco M, Theisen TC, Naor A, Rastogi S, Buchholz KR, Lorenzi H, Boothroyd JC. Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii. (2018) PLOS Pathogens. 14(1):e1006828.

Franco, M, Panas MW, Marino ND, Lee MC, Buchholz KR, Kelly FD, Bednarski JJ, Sleckman BP, Pourmand N, Boothroyd JC. (2016) A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. MBio. 7(1):02231-15.

Coffey MJ, Sleebs BE, Uboldi AD, Garnham A, Franco M, Marino ND, Panas MW, Ferguson DJ, Enciso M, O'Neill MT, Lopaticki S, Stewart RJ, Dewson G, Smyth GK, Smith BJ, Masters SL, Boothroyd JC, Boddey JA, Tonkin CJ. (2015) An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell. Elife. 4: e10809.

Franco, M, Shastri, AJ, Boothroyd, JC. (2014) Infection by Toxoplasma gondii specifically induces host c-Myc and the genes this pivotal transcription factor regulates. Eukaryotic cell. 13(4): 483-93.

Shastri, AJ, Marino, ND, Franco, M, Lodoen, MB, Boothroyd, JC. (2014) GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response. Infection and Immunity. 82 (6): 2595-605.

Lee, MW, Franco, M, Vargas, DM, Hudman, DA, White, SJ, Fowler, RG, Sargentini, NJ. (2014) A DinB mutation that sensitizes Escherichia coli to the lethal effects of UV and X-radiation. Mutation Research. 763-764:19-27.