William Francis Drew Bennett

Portrait of  William Francis Drew Bennett

  • Title
    Staff Scientist
  • Email
  • Phone
    (925) 422-6332
  • Organization
    Not Available


My research interests are in the area of molecular dynamics simulations of lipid membrane systems. I use free energy calculations and multiscale methods to characterize lipid bilayers at the molecular level. My current research areas include the investigation of drug-membrane interactions, ion channels, and protonation states of amphiphiles.

Ph.D. Biochemistry, University of Calgary (2013)

B.Sc. Biochemistry, University of Calgary (2007)

  1. Bennett, W.F.D., Shea, J.E., Tieleman, D.P. (2018) Phospholipid chain interactions with cholesterol drive domain formation in lipid membranes. Biophysical Journal. 114 (11), 2595-2605.
  2. Lu, S., Bennett, W.F.D., Ding, Y., Zhang, L., Fan, H.L., Zhao, D., Zheng, T., Ouyang, P., Li, J., Wu, Y., Xu, W., Chu, D., Yuan, Y., Heerklotz, H., Karttunen, M., Chen, P. (2015) Design and Characterization of a Multi-functional pH-triggered Peptide C8 for Selective Anticancer Activity. Advanced Healthcare Materials. 4:2709-2718. (Co-first author).
  3. Bennett, W.F.D., Tieleman, D.P. (2014) The importance of membrane defects – Lessons from simulations. Accounts of Chemical Research. 47:2244-2251.
  4. Bennett, W.F.D., MacCallum, J.L., Hinner, M.J., Marrink, S.J., Tieleman, D.P. (2009) A molecular view of cholesterol flip-flop and chemical potential in different membrane environments. J. Am. Chem. Soc. 131: 12714-12720.
  5. MacCallum, J.L., Bennett, W.F.D., and Tieleman, D.P. (2008) Distribution of amino acids in a lipid bilayer from computer simulations. Biophysical Journal 94: 3393-3404.

For a complete list of publications: https://scholar.google.com/citations?user=6hMN7lIAAAAJ&hl=en